Dr. Grotheer

Neural substrates of word and number categorization

Project C10 will evaluate how the brain supports word and number categorization, by further characterizing regions in the ventral visual stream that respond preferentially to each of these stimuli. We will i) elucidate if and how neural responses in word and number regions are impacted by the task the participants are performing, ii) investigate recent reports that number regions are challenging to identify across studies and provide a reliable fMRI localizer to overcome these challenges, iii) evaluate the emergence of number regions during childhood education and model this process in convolutional neural networks. By providing a better characterization of word and number regions, we will generate insight on visual categorization, as well as learning-induced changes in the brain. Moreover, as word and number regions in the ventral visual stream have been implicated in dyslexia and dyscalculia, the current project may facilitate future clinical work on these disorders.

project-related publications
Grotheer, M.*, Ambrus, G. G.*, & Kovács, G. (2016). Causal evidence of the involvement of the number form area in the visual detection of numbers and letters. Neuroimage, 132, 314-319. *authors contributed equally. find paper
Grotheer, M., & Kovács, G. (2014). Repetition probability effects depend on prior experiences. Journal of Neuroscience, 34(19), 6640-6646. find paper
Grotheer, M., Herrmann, K. H., & Kovács, G. (2016). Neuroimaging evidences of a bilateral representation for visually presented numbers. Journal of Neuroscience, 36(1), 88-97. find paper
Grotheer, M., Jeska, B., & Grill-Spector, K. (2018). A preference for mathematical processing outweighs the selectivity for Arabic numbers in the inferior temporal cortex. Neuroimage, 175, 188-200. find paper
Grotheer, M., Rosenke, M., Wu, H. et al. (2022). White matter myelination during early infancy is linked to spatial gradients and myelin content at birth. Nat Commun 13, 997. find paper
Grotheer, M., Rosenke, M., Wu, H., Kular, H., Querdasi, F.R., Natu, V., Yeatman, J.D., Grill-Spector, K. (2021a). Catch me if you can: Least myelinated white matter develops fastest during early infancy 2 3. bioRxiv, 2021.03.29.437583. find preprint
Grotheer, M., Yeatman, J.*, & Grill-Spector, K.* (2021). White matter fascicles and cortical microstructure predict reading-related responses in ventral temporal cortex. Neuroimage, 227, 117669. *senior authors contributed equally. find paper
Grotheer, M., Zhen, Z., Lerma-Usabiaga, G., & Grill-Spector, K. (2019). Separate lanes for adding and reading in the white matter highways of the human brain. Nature Communications, 10(1), 3675. find paper